Non-surgical anti-ageing treatment

Polynucleotide (PN) therapy is a cutting-edge non-surgical treatment that harnesses the power of DNA to restore and rejuvenate the skin. Adnova Clinics utilise modern treatments such as this to achieve the best results for our patients.

What is polynucleotide?

PN therapy involves injecting a solution derived from salmon or trout DNA into the skin. The solution stimulates collagen production, improves skin elasticity, and enhances overall skin texture. Polynucleotides are suitable for all skin types and can be used to address a range of concerns, including fine lines, wrinkles, and skin laxity. The treatment is administered through a series of injections that cause minimal discomfort and requires minimal downtime. This is a priority at Adnova Clinics, as it allows us to provide an optimum patient experience without sacrificing quality of care.

 

The science of polynucleotide treatments

A polynucleotide skin booster uses biological molecules rich in nutrients and antioxidants to improve skin health. This targets visible signs of ageing by working at a cellular level to promote skin regeneration. The treatment activates the skin’s natural repair processes, helping to improve skin tone and texture over time, resulting in a more youthful and radiant complexion. Get in touch if you have any questions. 

Here at Adnova we have a range of non-surgical treatments for you to choose from. These include Dermal fillers, Chemical peels, and Hydrafacials.

Polynucleotide Pricing

1 area
£250 (per session)
2 area
£450 (per session)
3 area
£650 (per session)
Packages
A minimum of 3 sessions is recommended per area for optimum results.
*treatment areas periocular, cheeks, forehead, neck, decollete, perioral etc

Polynucleotide Pricing

1 area
£250 (per session)
2 area
£450 (per session)
3 area
£650 (per session)
Packages
A minimum of 3 sessions is recommended per area for optimum results.
*treatment areas periocular, cheeks, forehead, neck, decollete, perioral etc

Who we are?

adnova team plastic surgeons

Testimonials

Wendy Murwill
11:09 29 Oct 25
My experience at Adnova has been amazing. From my initial consultation and throughout, the whole team has been welcoming and supportive. The clinic is spotless and comfortable.
Mr Simon Heppell at Adnova is a gifted and amazing surgeon. I would thoroughly recommend both Adnova Clinic and Mr Heppell to anyone.
Claire Rutherford
07:43 15 Oct 25
I had a mastopexy done here and I'm so pleased with the results! The clinic looked after me so well and I recommend to others!
Malindi Arengo-Jones
12:21 12 Oct 25
I took my daughter to Adnova to see Mr Biggs about a nasty hockey injury to her nose. After an excellent consultation, she decided to go ahead with the surgery. On arrival, the Adnova team was incredibly friendly and efficient. She was particularly nervous about the anaesthesia, but her anaesthetist Marcus Fletcher was outstanding with her. His calm manner and gentle confidence was exactly what she needed. We were sent home same day with everything we needed to keep her comfortable at home and the results have been amazing. The piezo method used by Mr Biggs meant that bruising and swelling was limited and her confidence has re-emerged. I had definitely underestimated the incredible effect this kind of surgery can have on self-confidence. I am incredibly grateful to the Adnova team, the amazing Mr Biggs and our unsung hero of the OR, Marcus Fletcher. Thank you.
Amber Du Plessis
11:36 01 Oct 25
Adnova is an excellent clinic. A very friendly and helpful reception. A very professional environment. The medical and aesthetic team are exceptional. I would highly recommend this clinic.
Leonie Tidy
22:08 27 Sep 25
Amazing clinic, Fantastic staff all round!
Ive had surgery with Simon Heppell the surgery really has changed my life given me the much needed look and confidence I always dreamed of.
The staff were fantastic from start to finish really made me feel at ease before, during and after the procedure.
Were on hand at anytime I needed during my recovery process.

Ive also had treatments with Anna at Adnova too, she absolutely brilliant and have become a regular client of hers.
See All Reviews

Book a Consultation

Speak to a qualified and accredited medical professional today. The team at Adnova Clinics provide advice and treatments tailored to your needs, and it all starts with a consultation to discuss your goals.

Book a Consultation

Frequently Asked Questions

In most cases, this treatment lasts for approximately 6 months. Multiple sessions can be used to maintain the effects of polynucleotide therapy over longer periods. 

Typically polynucleotide treatments are administered in a series of treatments spaced 3-4 weeks apart. The results of this treatment are gradual and long lasting. Patients can expect improved skin texture, tone and overall appearance over several months.  

Yes, indeed! PN’S serve as an excellent complement to various other treatments such as dermal fillers, chemical peels and surgery. They are renowned for their unique “skin priming” effect, preparing the skin for other treatments and enhancing their effectiveness. When used after other procedures, they can further optimise the results.  

Pn’s are considered extremely safe. After treatment, temporary effects like skin swelling and redness may occur, but subside within a few hours. There might be minimal bleeding or itchiness and swelling at the treatment sites. Occasional bruising may also occur.